| Clinical Infection and Immunity, ISSN 2371-4972 print, 2371-4980 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, Clin Infect Immun and Elmer Press Inc |
| Journal website https://cii.elmerpub.com |
Editorial
Volume 10, Number 2, June 2025, pages 25-28
Collinsella and Prevotella: Mixed Systemic Actions of a Dynamic Duo
Table
| Feature | Collinsella | Prevotella |
|---|---|---|
| SCFAs: short-chain fatty acids. | ||
| Gram stain | Gram-positive | Gram-negative |
| Shape | Rod-shaped | Rod-shaped |
| Spore formation | Non-spore-forming | Non-spore-forming |
| Motility | Non-motile | Non-motile |
| Oxygen requirement | Anaerobic | Anaerobic, some species are aerotolerant |
| Habitat | Human gut microbiota | Oral cavity, gastrointestinal tract, female genital tract |
| Temperature | Optimal growth at 37 °C | Optimal growth at 37 °C |
| pH | Thrives at pH 7 | Thrives at 6.5 to 7.5 |
| Metabolism | Breaks down complex carbohydrates and proteins, producing SCFAs and ammonia | Fermentative, producing SCFAs such as acetate and propionate |
| Lipids | Major fatty acids: C16:0, C18:1n9, C18:2n6 | Branched-chain fatty acids, methyl-branched fatty acids, straight-chain saturated and unsaturated fatty acids |
| Pigmentation | Not typically pigmented | Some species produce brown or black pigmented colonies on blood agar |