Clin Infect Immun

Clinical Infection and Immunity, ISSN 2371-4972 print, 2371-4980 online, Open Access

Article copyright, the authors; Journal compilation copyright, Clin Infect Immun and Elmer Press Inc

Journal website https://cii.elmerpub.com

Original Article

Volume 10, Number 1, March 2025, pages 18-23

Platelet Counts Variation and Platelet Indices According to the Severity and Outcome of COVID-19

**Table 1.** Distribution of Sociodemographic, Clinical and Biological Characteristics of Patients
Variables	Frequency, n	Percentage, %
Gender
Male	193	58.10
Female	139	41.90
Total	332	100.00
Sex ratio = 1.39
Age group
< 30 years	28	8.40
30 - 60 years	135	40.70
> 60 years	169	50.90
Total	332	100.00
Median age: 60 years
Clinical forms
Non-severe
Mild	168	50.60
Moderate	63	18.98
Severe
Severe	52	15.66
Critical	49	14.76
Outcome
Survival	293	88.25
Death	39	11.75
Platelet count
< 150 × 10⁹/L	29	8.74
150 - 450 × 10⁹/L	275	82.83
> 450 × 10⁹/L	28	8.43

Table 1. Distribution of Sociodemographic, Clinical and Biological Characteristics of Patients

Variables

Frequency, n

Percentage, %

Gender

Male

193

58.10

Female

139

41.90

Total

332

100.00

Sex ratio = 1.39

Age group

< 30 years

8.40

30 - 60 years

135

40.70

> 60 years

169

50.90

Total

332

100.00

Median age: 60 years

Clinical forms

Non-severe

Mild

168

50.60

Moderate

18.98

Severe

15.66

Critical

14.76

Outcome

Survival

293

88.25

Death

11.75

Platelet count

< 150 × 10⁹/L

8.74

150 - 450 × 10⁹/L

275

82.83

> 450 × 10⁹/L

8.43

**Table 2.** Difference in Age, Gender, Clinical Forms, and Platelet Count and Indices Between Severe and Non-Severe COVID-19 Patients
Variables	Clinical forms	P-value
COVID-19: coronavirus disease 2019; MPV: mean platelet volume; PCT: plateletcrit; PDW: platelet distribution width.
Age groups				0.001
< 60 years	24 (23.80)	139 (60.20)	163 (49.10)
> 60 years	77 (76.20)	92 (39.80)	169 (50.90)
Total	101 (30.40)	231 (69.60)	332 (100.00)
Gender				0.001
Female	24 (23.80)	115 (49.80)	139 (41.90)
Male	77 (76.20)	116 (50.20)	193 (58.10)
Total	101 (30.40)	231 (69.60)	332 (100.00)
Platelet count				0.329
< 150 × 10⁹/L	12 (11.90)	17 (7.40)	29 (8.80)
150 - 450 × 10⁹/L	77 (76.20)	198 (85.70)	275 (82.80)
> 450 × 10⁹/L	12 (11.90)	16 (6.90)	28 (8.40)
Total	101 (30.40)	231 (69.60)	332 (100.00)
Platelet’s indices
MPV	10.53	10.42	10.47	0.5
PDW	14.85	12.72	13.78	0.001
PCT	0.62	0.29	0.45	0.54

Table 2. Difference in Age, Gender, Clinical Forms, and Platelet Count and Indices Between Severe and Non-Severe COVID-19 Patients

Variables

Clinical forms

P-value

Severe, n (%)

Non-severe, n (%)

Total, N (%)

COVID-19: coronavirus disease 2019; MPV: mean platelet volume; PCT: plateletcrit; PDW: platelet distribution width.

Age groups

0.001

< 60 years

24 (23.80)

139 (60.20)

163 (49.10)

> 60 years

77 (76.20)

92 (39.80)

169 (50.90)

Total

101 (30.40)

231 (69.60)

332 (100.00)

Gender

0.001

Female

24 (23.80)

115 (49.80)

139 (41.90)

Male

77 (76.20)

116 (50.20)

193 (58.10)

Total

101 (30.40)

231 (69.60)

332 (100.00)

Platelet count

0.329

< 150 × 10⁹/L

12 (11.90)

17 (7.40)

29 (8.80)

150 - 450 × 10⁹/L

77 (76.20)

198 (85.70)

275 (82.80)

> 450 × 10⁹/L

12 (11.90)

16 (6.90)

28 (8.40)

Total

101 (30.40)

231 (69.60)

332 (100.00)

Platelet’s indices

MPV

10.53

10.42

10.47

0.5

PDW

14.85

12.72

13.78

0.001

PCT

0.62

0.29

0.45

0.54

**Table 3.** Difference in Age, Gender, Clinical Forms, and Platelet Count and Indices Between Survivors and Non-Survivors of Patients With COVID-19
Variables	Disease evolution	P-value
COVID-19: coronavirus disease 2019; MPV: mean platelet volume; PCT: plateletcrit; PDW: platelet distribution width.
Age group				0.001
< 60 years	7 (17.90)	156 (53.40)	163 (49.10)
> 60 years	32 (82.10)	137 (46.60)	169 (50.90)
Total	39 (11.70)	293 (88.30)	332 (100.00)
Gender				0.001
Female	8 (20.50)	131 (44.50)	139 (41.90)
Male	31 (79.50)	162 (55.50)	193 (58.10)
Total	39 (11.70)	293 (88.30)	332 (100.00)
Platelet count				0.13
< 150 × 10⁹/L	6 (15.40)	23 (7.90)	29 (8.80)
150 - 450 × 10⁹/L	32 (82.00)	243 (82.90)	275 (82.80)
> 450 × 10⁹/L	01 (2.60)	27 (9.20)	28 (8.40)
Total	39 (11.70)	293 (88.30)	332 (100.00)
Platlet’s indices
MPV	10.60	10.43	10.47	0.53
PDW	15.29	13.13	13.78	0.005
PCT	1.31	0.33	0.45	0.67

Table 3. Difference in Age, Gender, Clinical Forms, and Platelet Count and Indices Between Survivors and Non-Survivors of Patients With COVID-19

Variables

Disease evolution

P-value

Non-survivors, n (%)

Survivors, n (%)

Total, N (%)

COVID-19: coronavirus disease 2019; MPV: mean platelet volume; PCT: plateletcrit; PDW: platelet distribution width.

Age group

0.001

< 60 years

7 (17.90)

156 (53.40)

163 (49.10)

> 60 years

32 (82.10)

137 (46.60)

169 (50.90)

Total

39 (11.70)

293 (88.30)

332 (100.00)

Gender

0.001

Female

8 (20.50)

131 (44.50)

139 (41.90)

Male

31 (79.50)

162 (55.50)

193 (58.10)

Total

39 (11.70)

293 (88.30)

332 (100.00)

Platelet count

0.13

< 150 × 10⁹/L

6 (15.40)

23 (7.90)

29 (8.80)

150 - 450 × 10⁹/L

32 (82.00)

243 (82.90)

275 (82.80)

> 450 × 10⁹/L

01 (2.60)

27 (9.20)

28 (8.40)

Total

39 (11.70)

293 (88.30)

332 (100.00)

Platlet’s indices

MPV

10.60

10.43

10.47

0.53

PDW

15.29

13.13

13.78

0.005

PCT

1.31

0.33

0.45

0.67